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Publications

1.    Epstein, R.J., Kelly, S.A., Cook, M., Bateman, A., Paddick, I., Kam, K.C., Dunn, P., Hanham I.W., Dale R.D., Price P.M. (1996). Active minimisation of radiation scatter during breast radiotherapy: management implications for young patients with good-prognosis primary neoplasms. Radiotherapy and Oncology 40 69-74

 

2.    DeClemente A.J., and Paddick, I. (1997). Errors in three-dimensional doses calculated from a two-dimensional database - case report: wedged fields at 6MV. Phys. Med. Biol 42 1197-1202

 

3.    Paddick, I. (2000). A Simple Scoring Ratio to Index the Conformity of Radiosurgical Treatment Plans.

Journal of Neurosurgery (Suppl 3) 93 Dec 

(This conformity index is used at an increasing number of international centres, and is cited in over 800 other papers)

 

4.    Paddick, I., and Lippitz, B. (2006). A simple Dose Measurement Tool to Compliment the Conformity Index. Journal of Neurosurgery (Suppl) 105 194-201 

 

5.    Christopoulou, A., Retsas, S., Kingsley, D., Paddick, I., and Lindquist, C. (2006). Integration of gamma knife surgery in the management of cerebral metastases from melanoma. Melanoma Research, 16:51–57

 

6.    The Gamma Knife Perfexion and comparisons with its predecessors. Lindquist, C., and Paddick, I. Neurosurgery 61:ONS-130–141, 2007

 

7.    McDermott, M.W., Sneed, P.K., Huang, K., Ma, L., Jensen, R.L., Paddick, I. (2009). Radiosurgery 7: Karger (co-editor) 

 

8.    Giller, C.A., Fiedler, J.A., Gagnon, G.J., and Paddick, I. (2009). Radiosurgical Planning: Gamma Tricks and Cyber Tips. Wiley-Blackwell

 

9.    Lippitz, B., Lindquist, C., Paddick, I., Peterson, D., O’Neill, K. and Beaney, R. (2013). Stereotactic Radiosurgery in the Treatment of Brain Metastases: The Current Evidence. Cancer Treatment Reviews

 

10.    Hopewell, J.W., Millar, W.T., Paddick, I. and Lindquist, C. (2013). Impact of decaying dose-rate in gamma knife radiosurgery (letter to the editor). J Radiosurg SBRT 2: 251-253. 

 

11.    Paddick, I. and Motti, E. (2013) Targeting and Conformality in Arteriovenous Malformation Radiosurgery: Prog Neurol Surg. Basel, Karger, vol 27, pp 35–48 

 

12.    Torrens, M., Chung, C., Chung, H-T., Hanssens, P., Jaffray, D., Kemeny, A., Larson, D., Levivier, M., Lindquist, C., Lippitz, B., Novotny J., Paddick, I., Prasad, D., and Yu. C.P. (2014). Standardization of terminology in stereotactic radiosurgery: Report from the Standardization Committee of the International Leksell Gamma Knife Society: Special topic. Journal of neurosurgery. 121 Suppl 2 p2-15 

 

13.    Chung, C., Torrens, M., Paddick, I., Ryu, S., Hanssens, P. and Jaffray D. (2015) Radiosurgery Nomenclature: A Confusion of Tongues. International Journal of Radiation Oncology Biology Physics 92 (3), 512-513

 

14.    Benmakhlouf, H., Johansson, J., Paddick, I. and Andreo, P. (2015). Monte Carlo calculated and experimentally determined output correction factors for small field detectors in Leksell Gamma Knife Perfexion beams. Physics in medicine and biology 60 (10), 3959

 

15.    Millar, W.T., Hopewell, J.W., Paddick, I., Lindquist, C., Nordströn, H., Lidberg, P. (2015). The role of the concept of biologically effective dose (BED) in treatment planning in radiosurgery. Phys Med. Sep;31(6):627-33

 

16.    Rojas-Villabona, A., Miszkiel, K., Kitchen, N., Jäger, R., Paddick I. (2016) Evaluation of the stability of the stereotactic Leksell Frame G in Gamma Knife radiosurgery. Journal of Applied Clinical Medical Physics 17 (3)

 

17.    Rojas-Villabona, A., Kitchen, N., Paddick I (2016) Investigation of dosimetric differences between the TMR 10 and convolution algorithm for Gamma Knife stereotactic radiosurgery. Journal of Applied Clinical Medical Physics 17 (6)

 

18.    Zain A. Husain, Arjun Sahgal, Antonio De Salles, Melissa Funaro, Janis Glover, Motohiro Hayashi, Masahiro Hiraoka, Marc Levivier, Lijun Ma, Roberto Martínez-Alvarez, Ian Paddick, Jean Régis, Ben J. Slotman, and Samuel Ryu, (2017) Stereotactic body radiotherapy for de novo spinal metastases: systematic review. International Stereotactic Radiosurgery Society practice guidelines. Journal of Neurosurgery 2017.1.SPINE16684

 

19.    S Myrehaug, A Sahgal, M Hayashi, M Levivier, L Ma, R Martinez, Ian Paddick, Jean Régis, Samuel Ryu, Ben Slotman, Antonio De Salles. Reirradiation spine stereotactic body radiation therapy for spinal metastases: systematic review: International Stereotactic Radiosurgery Society practice guidelines. Journal of Neurosurgery: Spine 27 (4), 428-435

 

20.    May N Tsao, Arjun Sahgal, Wei Xu, Antonio De Salles, Motohiro Hayashi, Marc Levivier, Lijun Ma, Roberto Martinez, Jean Régis, Sam Ryu, Ben J Slotman, Ian Paddick: Stereotactic radiosurgery for vestibular schwannoma: International Stereotactic Radiosurgery Society (ISRS) Practice Guideline. J Radiosurg SBRT 5(1)

 

21.    Nuria E Martínez-Moreno, Arjun Sahgal, Antonio De Salles, Motohiro Hayashi, Marc Levivier, Lijun Ma, Ian Paddick, Jean Régis, Sam Ryu, Ben J Slotman, Roberto Martínez-Álvarez, Stereotactic radiosurgery for tremor: systematic review: International Stereotactic Radiosurgery Society practice guidelines. Journal of Neurosurgery 2018 23(2) 1-12

 

22.    Samuel T Chao, Antonio De Salles, Motohiro Hayashi, Marc Levivier, Lijun Ma, Roberto Martinez, Ian Paddick, Jean Régis, Samuel Ryu, Ben J Slotman, Arjun Sahgal. Stereotactic Radiosurgery in the Management of Limited (1-4) Brain Metasteses: Systematic Review and International Stereotactic Radiosurgery Society Practice Guidelines. Neurosurgery 2017 11(3) 

 

23.    Aileen McGonigal, Arjun Sahgal, Antonio De Salles, Motohiro Hayashi, Marc Levivier, Lijun Ma, Roberto Martinez, Ian Paddick, Samuel Ryu, Ben J Slotman, Jean Régis: Radiosurgery for epilepsy: Systematic review and International Stereotactic Radiosurgery Society (ISRS) practice guideline. Epilepsy research 2017 Vol 137 123-131

 

24.    DJ Eaton, J Lee, I Paddick. Stereotactic radiosurgery for multiple brain metastases: Results of multi-centre benchmark planning studies. Practical Radiation Oncology 2017

 

25.    DJ Eaton, J Lee, R Patel, AE Millin, I Paddick, C Walker. Stereotactic radiosurgery for benign brain tumours: Results of multi-centre benchmark planning studies. Practical Radiation Oncology 2018

 

26.    Cheng-Chia Lee, Daniel M Trifiletti, Arjun Sahgal, Antonio DeSalles, Laura Fariselli, Motohiro Hayashi, Marc Levivier, Lijun Ma, Roberto Martinez, Ian Paddick, Jean Régis

Samuel Ryu, Ben J Slotman, Jason Sheehan: Stereotactic Radiosurgery for Benign (World Health Organization Grade I) Cavernous Sinus Meningiomas—International Stereotactic Radiosurgery Society (ISRS) Practice Guideline: A Systematic Review. Neurosurgery 2018

 

27.    Constantin Tuleasca, Jean Régis, Arjun Sahgal, Antonio De Salles, Motohiro Hayashi, Lijun Ma, Roberto Martinez-Alvarez, Ian Paddick, Samuel Ryu, Ben J Slotman, Marc Levivier: Stereotactic radiosurgery for trigeminal neuralgia: International Society of Stereotactic Radiosurgery (ISRS) Practice Guidelines. Journal of Neurosurgery 2018

 

28.    Cafeteria approach to management of trigeminal neuralgia: stereotactic radiosurgery as a preferred option Response

C Tuleasca, J Regis, A Sahgal, A De Salles, M Hayashi, Lijun Ma, Roberto Martinez-Alvarez, Ian Paddick, Samuel Ryu, Ben J Slotman, Marc Levivier: Journal of Neurosurgery 130 (ARTICLE), 1029-1030

 

29.    Leksell Gamma Knife Society and radiosurgery: a legacy and a vision for the future

C Chung, D Prasad, M Torrens, I Paddick, P Hanssens, D Kondziolka, D A Jaffray

Journal of Neurosurgery 129 (Suppl1), 2-4

 

30.    A novel index for assessing treatment plan quality in stereotactic radiosurgery

A Dimitriadis, I Paddick. Journal of Neurosurgery 129 (Suppl1), 118-124

 

31.    Personal perspectives on the evolution of radiation therapy and future outlook for SRS. I Paddick Journal of Radiosurgery and SBRT 2018 Vol 5 (2)

 

32.    Evolution of gamma knife capsulotomy for intractable obsessive-compulsive disorder

Euripedes C Miguel, Antonio C Lopes, Nicole CR McLaughlin, Georg Norén, André F Gentil, Clement Hamani, Roseli G Shavitt, Marcelo C Batistuzzo, Edoardo FQ Vattimo, Miguel Canteras, Antonio De Salles, Alessandra Gorgulho, João Victor Salvajoli, Erich Talamoni Fonoff, Ian Paddick, Marcelo Q Hoexter, Christer Lindquist, Suzanne N Haber, Benjamin D Greenberg, Sameer A Sheth. Molecular psychiatry 24 (2), 218

 

33.    Effects of variations in overall treatment time on the clonogenic survival of V79-4 cells: Implications for radiosurgery. S Hallgren, MA Hill, JM Thompson, A Elliott, I Paddick, B Jones, J W Hopewell. Journal of radiosurgery and SBRT 6 (1), 1

 

34.    Letter to the Editor. Predictors for radiation toxicity and tumor control. I Paddick, A Dimitriadis. Journal of neurosurgery 1 (aop), 1-2

 

35.    Establishment of a Therapeutic Ratio for Gamma Knife Radiosurgery of Trigeminal Neuralgia: The Critical Importance of Biologically Effective Dose Versus Physical Dose

C Tuleasca, I Paddick, JW Hopewell, B Jones, WT Millar, H Hamdi, Denis Porcheron, Marc Levivier, Jean Régis. World neurosurgery. 2019. In press.

 

36.    Automatic Segmentation of Vestibular Schwannoma from T2-Weighted MRI by Deep Spatial Attention with Hardness-Weighted Loss. G Wang, J Shapey, W Li, R Dorent, A Demitriadis, S Bisdas, I Paddick, Robert Bradford, Shaoting Zhang, Sébastien Ourselin, Tom Vercauteren. International Conference on Medical Image Computing and Computer-Assisted Intervention. MICCAI 2019 pp 264-272.

 

37.    Letter: Treatment Outcomes and Dose Rate Effects Following Gamma Knife Stereotactic Radiosurgery for Vestibular Schwannomas. I Paddick, JW Hopewell, T Klinge, CS Graffeo, B Pollock, P Sneed. Neurosurgery 10.1093/neuros/nyz547 

 

38.    Kotecha R, Sahgal A, Rubens M, De Salles A, Fariselli L, Pollock BE, Levivier M, Ma L, Paddick I, Regis JM, Sheehan J, Yomo S, Suh J, Stereotactic Radiosurgery for Non-Functioning Pituitary Adenomas: Meta-Analysis and International Society of Stereotactic Radiosurgery (ISRS) Practice Opinion. Neuro Oncol 2020 Mar 5;22(3):318-332 

 

39.    Marchetti M, Sahgal A, De Salles A,  Levivier M, Ma L, Paddick I, Pollock BE, Regis JM, Sheehan J, Suh J, Yomo S, Fariselli L, Stereotactic Radiosurgery for Intracranial Noncavernous Sinus Benign Meningioma: International Stereotactic Radiosurgery Society Systematic Review, Meta-Analysis and Practice Guideline. Neurosurgery. 2020 May 28

 

40.    Paddick I, Grishchuk D, Dimitriadis A, IntuitivePlan inverse planning performance evaluation for Gamma Knife radiosurgery of AVMs: J Appl Clin Med Phys 2020; 1–7 DOI: 10.1002/acm2.12973  

 

41.    Graffeo CS, Sahgal A, De Salles A, Fariselli L, Levivier M, Ma L, Paddick I, Regis JM, Sheehan J, Suh J, Yomo S, Pollock BE: Radiosurgery for Spetzler-Martin Grade I and II Arteriovenous Malformations: International Society of Stereotactic Radiosurgery (ISRS) Practice Guideline.Neurosurgery. 2020 Feb 17.

 

42.    S Thrower, KA Al Feghali, D Luo, I Paddick, KK Brock, C Chung: MR Slice Thickness Impacts Detection and Delineation of Brain Metastases for Treatment Determination, Radiosurgery Treatment Planning and Follow-Up. IJROBP 108 (3), e680

 

43.    SE Combs, BG Baumert, M Bendszus, A Bozzao, M Brada, L Fariselli, A Fiorentino, U Ganswindt, A L Grosu, F L Lagerwaard, M Niyazi, T Nyholm, I Paddick, D C Weber, C Belka, G Minniti: ESTRO ACROP Guideline for Target Volume Delineation of Skull Base Tumors. Radiotherapy and Oncology 156, 80-94

 

44.    Paddick I, Dimitriadis A, Cameron A: Extracranial dose and the risk of radiation-induced malignancy after intracranial stereotactic radiosurgery: is it time to establish a therapeutic reference level? Acta Neurochirurgica 1-9. 2020 https://doi.org/10.1007/s00701-020-04664-4

 

45.    JW Hopewell, I Paddick, B Jones, T Klinge: Letter to the Editor. Biologically effective dose and the treatment of AVMs. Journal of Neurosurgery 1 (aop), 1-4

 

46.    A R Villabona, M Sokolska, E De Vita, M Murphy, T Solbach, J Grieve, P Rangi, Y Suzuki, M JP Van Osch, D Atkinson, E Biondetti, K Shmueli, X Golay, I Paddick, N Kitchen, H R Jäger: Planning of gamma knife radiosurgery (GKR) for brain arteriovenous malformations using triple magnetic resonance angiography (triple-MRA). British Journal of Neurosurgery 1-11

 

47.    Redmond KJ, De Salles A, Fariselli L, Levivier M, Ma L, Paddick I, Pollock BE, Regis JM, Sheehan J, Suh J, Yomo S, Sahgal A Stereotactic Radiosurgery for Post-Operative Metastatic Surgical Cavities: A Critical Review and International Society of Stereotactic Radiosurgery (ISRS) Practice Guidelines. IJROBP In Press. DOI: https://doi.org/10.1016/j.ijrobp.2021.04.016

 

48.    S Thrower, KA Al Feghali, D Luo, I Paddick, P Hou, T Briere, J Li, MF McAleer, SL McGovern, Kristina D Woodhouse, DN Yeboa KK Brock, C Chung: The impact of slice thickness on contours of brain metastases for stereotactic radiosurgery: MRI slice thickness for SRS. Advances in Radiation Oncology 2021. https://doi.org/10.1016/j.adro.2021.100708

Research

We have an impressive track record of research in the field of SRS

Our work includes Planning Indices, Radiobiology, Device Comparisons and Radiation Protection.